Loss of enzyme reduces neural activity in Angelman syndrome

5th March, 2010 - Posted by admin -

Angelman syndrome (AS) is a debilitating neurological disorder characterized by mental retardation and a high frequency of autism. Researchers have now found that the gene mutation underlying AS appears to affect the ability of neurons to communicate and to properly develop during the first few years of life, a time when brain activity is “rewired” by external stimuli.